| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | Orange Park | 42.00 | Sermons, Restall, Chambers, Thomas | FHSAA 3A Region 1 | May 1, 2021 |
| 2 | Palatka | 42.66 | Nelson, Clark, Newman, Passmore | FHSAA 2A District 5 | Apr 20, 2021 |
| 3 | Fleming Island | 42.98 | Harris, Grind, Cook, Singleton | Bear Classic Track & Field Meet | Mar 13, 2021 |
| 4 | Bartram Trail | 43.17 | Jones, Stiles, Weatherly, Archer | Danny Brown Invitational | Feb 27, 2021 |
| 5 | St. Augustine | 43.85 | Hamilton, Cooper, Harris, Stanley | Stinger Invitational | Mar 31, 2021 |
| 6 | Matanzas | 44.93 | Headley, Gaines, Cundiff, Souverain | FHSAA 3A District 4 | Apr 14, 2021 |
| 7 | Nease | 45.26 | Heard, Mahoney, Gill, Williams | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| 8 | Menendez | 45.30 | Newsome, Butler, Davis, Jones | Providence Invitational 2021 | Mar 19, 2021 |
| 9 | Middleburg | 47.68 | Villafane, Floyd, Delpha, Senear | Clay County Championships | Mar 26, 2021 |
| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | St. Augustine | 49.73 | Johnson, Stephens, Smith, Barton | FHSAA 3A Region 1 | May 1, 2021 |
| 2 | Middleburg | 50.16 | Kidson, Morelus, Russell, Mckenzie | FHSAA 3A Region 1 | May 1, 2021 |
| 3 | Fleming Island | 50.82 | Deas, Ortiz, Martin, Amsden | FHSAA 4A District 2 | Apr 21, 2021 |
| 4 | Bartram Trail | 50.86 | Modozie, Annis, Cagnani, Bachmann | FHSAA 4A District 2 | Apr 21, 2021 |
| 5 | Palatka | 51.25 | Edwards, Passmore, Jamya, Harvey | FHSAA 2A Region 2 | May 1, 2021 |
| 6 | Menendez | 51.31 | Goodwin, Tompkins, Harris, Stewart | FHSAA 2A Region 2 | May 1, 2021 |
| 7 | Matanzas | 51.37 | Engblom, Walker, Felton, Catlin | FHSAA 3A Region 1 | May 1, 2021 |
| 8 | Orange Park | 51.55 | Harris, Johnson, Johnson, Williams | Clay County Championships | Mar 26, 2021 |
| 9 | Nease | 53.31 | Gregory, Whitehead, Gould, Murphy | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | Bartram Trail | 3:23.83 | Phillips, Keener, Stiles, Kash | FHSAA 4A Region 1 | May 1, 2021 |
| 2 | Fleming Island | 3:27.27 | Huynh, Davis, Lewis, Bendig | FHSAA 4A District 2 | Apr 21, 2021 |
| 3 | Orange Park | 3:28.23 | Childs, Thomas, Arias, Brown | FHSAA 3A Region 1 | May 1, 2021 |
| 4 | Palatka | 3:31.67 | Clark, Nelson, Newman, Bryant | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| 5 | Nease | 3:31.78 | Gill, De La Torre, Vega, Ingle | FHSAA 4A District 2 | Apr 21, 2021 |
| 6 | Matanzas | 3:33.52 | Souverain, Miller, Friendly, Gaines | FHSAA 3A Region 1 | May 1, 2021 |
| 7 | Middleburg | 3:41.07 | Pena, Rhoads, Bowerman, Shaw | FHSAA 3A District 3 | Apr 21, 2021 |
| 8 | St. Augustine | 3:43.16 | Cooper, Hamilton, Harris, Stanley | Stinger Invitational | Mar 31, 2021 |
| 9 | Menendez | 3:46.69 | Courter, Jones, Quintero, Lovett | Creekside Tri Meet | Apr 9, 2021 |
| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | Bartram Trail | 4:09.06 | Greene, Hanna, Henley, Bachmann | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| 2 | Fleming Island | 4:11.42 | Flores, Larson, Thompson, Amsden | FHSAA 4A Region 1 | May 1, 2021 |
| 3 | St. Augustine | 4:17.74 | Geter, Johnson, Barton, Stephens | FHSAA 3A Region 1 | May 1, 2021 |
| 4 | Orange Park | 4:19.51 | Johnson, Johnson, Williams, Harris | Clay County Championships | Mar 26, 2021 |
| 5 | Matanzas | 4:23.03 | Walker, Catlin, Hulsey, Allen | FHSAA 3A Region 1 | May 1, 2021 |
| 6 | Nease | 4:27.25 | Baptiste, Cuevas, Robinson, Murphy | East Coast Classic | Feb 26, 2021 |
| 7 | Palatka | 4:28.21 | Ford, Passmore, Jamya, Edwards | FHSAA 2A Region 2 | May 1, 2021 |
| 8 | Middleburg | 4:29.73 | Burt, Mckenzie, Morelus, Mussante | Bob Hayes Classic | Mar 20, 2021 |
| 9 | Menendez | 4:43.85 | Massey, Lopez, Yee, Harris | Stinger Invitational | Mar 31, 2021 |
| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | Nease | 7:58.23 | Kinsey, Cartwright, De La Torre, Vega | FHSAA Class 4A Track & Field State Championships | May 8, 2021 |
| 2 | Fleming Island | 7:59.64 | Bendig, Lyon, Scherer, McDade | FHSAA Class 4A Track & Field State Championships | May 8, 2021 |
| 3 | Bartram Trail | 7:59.76 | White, Popik, McDonald, Arias | FHSAA 4A Region 1 | May 1, 2021 |
| 4 | St. Augustine | 8:16.92 | Hacking, Hett, Schein, Koppman | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| 5 | Menendez | 8:35.67 | Fuentes, Kelsey, Jones, Courter | FHSAA 2A Region 2 | May 1, 2021 |
| 6 | Middleburg | 8:41.49 | Moore, Anderson, Lima, Rhoads | Stanton College Prep Track & Field Meet | Mar 22, 2021 |
| 7 | Matanzas | 9:07.50 | Spooner, Smith, hyatt, Drost | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| 8 | Palatka | 9:17.17 | Passmore, Seyler, Bryant, Holland | SFHS Mini Meet #1 | Feb 18, 2021 |
| 9 | Orange Park | 9:29.71 | Bartley, Benitez, Wharton, Shinhoster | Don Hall Invitational / St. John River Conference | Apr 9, 2021 |
| Team | Time | Athletes | Meet | Meet Date | |
|---|---|---|---|---|---|
| 1 | Bartram Trail | 9:51.80 | Ivey, Henley, Rodriguez, Harris | FHSAA 4A Region 1 | May 1, 2021 |
| 2 | Fleming Island | 9:53.06 | Kortright, Knotts, Thompson, Scherer | FHSAA 4A Region 1 | May 1, 2021 |
| 3 | St. Augustine | 9:58.22 | Hacking, Woodruff, McElhone, Barber | FHSAA 3A District 3 | Apr 21, 2021 |
| 4 | Nease | 10:40.62 | Cuevas, Etique, Murphy, Harrison | FHSAA 4A District 2 | Apr 21, 2021 |
| 5 | Middleburg | 10:44.44 | Mathis, Mussante, Wager, Cassada | FHSAA 3A Region 1 | May 1, 2021 |
| 6 | Matanzas | 11:25.90 | Marshall, Irving, Wodchis, Rodriquez | Deland HS Big D Relays 2021 | Mar 13, 2021 |
| 7 | Orange Park | 11:43.37 | Carter, Davila, Menendez, Wilson | FHSAA 3A District 3 | Apr 21, 2021 |
| 8 | Menendez | 11:44.15 | Fuentes, Kemp, Reinhold, Yee | FHSAA 2A District 5 | Apr 20, 2021 |
| 9 | Palatka | 12:00.26 | Passmore, Nettle, Ford, Taylor | SFHS Mini Meet #1 | Feb 18, 2021 |